5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor as well as metabolic intermediate in the biosynthesis of the neurotransmitters serotonin and melatonin from tryptophan. Tryptophan is an amino acid that converts to 5 HTP (5-hydroxytryptophan) which then can convert to serotonin, an important brain chemical involved in mood, behavior, appetite, and sleep. Low serotonin levels may lead to addictive behavior such as gambling or other habits caused by weak will power. Serotonin is known as 5-HT, or 5-hydroxytryptamine, and is found in many places in the body particularly the brain, gastrointestinal system, and blood cells. Once serotonin is made, the pineal gland is able to convert it at night into melatonin, the sleep-inducing hormone. Tryptophan, 5 HTP, and melatonin are available for sale as dietary supplements, but not serotonin. Continue reading →